Unlock Conductor Anima in your Sanctum Tank in Shadowlands by spending 1000 Anima and 1 Redeemed Soul.
Sanctum upgrades are not free and to access Conductor Anima you will need 1 Anima and a Redeemed Soul. The first chapter of your Covenent campaign will task you with cultivating 000 Anima and collecting 1000 Redeemed Souls before granting you access to your Sanctum upgrades, so that you can technically unlock the Anima Conductor as your first upgrade. . If you choose to unlock the Transport Network or the Adventure Command Table first, all you'll need is another 5 anima, as the initial unlock for both will only cost you a traded soul each.
Once you've unlocked the Anima conductor, it will appear on your map and minimap as a sort of runic "T". You'll have a quest to interact with him, so go ahead and talk to the relevant NPC in your Covenant. They will give you a basic overview of how the Anima Conductor works, and then send you on your merry way. It's not much, so let me go into a little more detail on how the Anima Conductor works in Shadowlands.
Initially, you will have access to two different “nodes” to the Anima conductor, and for 25 Anima you can feed one with an Anima stream for the day. Each node is associated with a different event, so hover over the node to find out what it is. The first two nodes will be a Rare Chest and a Rare Boss, and both will reward you with at least a handful of Anima items, Vendor Scraps, and Grateful Offerings. These Gratitude Offers are the key item here, as they cannot be earned elsewhere, and are a currency you will need to stockpile if you plan to purchase your Alliance's Mount, Familiar, and / or Fame Transmog.
Once you direct Anima to one of the nodes, it will remain active for a whole 24 hours, even after the daily reset. You'll also generate a charge at the bottom of your Anima Conductor, and at ten o'clock you can choose an Anima flow to boost. Reinforcement unlocks that particular node permanently, although you will only be able to collect the reward once per day.
You can channel an Anima stream to any unpowered node after the daily reset, which means you can double your rewards since any active node lasts 24 hours. After the daily reset, it will refresh its reward and stay active until it is active for its entire duration, so you can channel Anima to the node you did not power the day before and collect both rewards. You'll want to power a new node to generate a charge in your Anima Conductor whenever you can, as you'll ultimately have six nodes to collect rewards once you've fully upgraded the Anima Conductor. Upgrading a node means you can farm more Grateful Offers per day, meaning you'll be able to collect items from your Fame Vendor once you unlock them.