Many of these weapons you are likely to unlock on your first try. If you complete each mission with a silent assassin rank, you can easily gain 5 mastery levels in a single round. If you aim for Silent Assassin, Suit Only, you will get even more Mastery EXP. But you can also play the levels in any order you like - so these are the items (and missions) you'll want to grind first. Some of these items are invaluable for Silent Assassin executions on Master difficulty.
12 best levels of Hitman | Beginner's Guide | How to postpone progress | Best Unlockable Items | How To Take The Mile High Drop Challenge | Dubai Guide | How to unlock the Dartmoor safe | File Puzzle Guide | How To Solve The Dartmoor Murder Mystery | Guide "Means, motivation and opportunity" | How to meet the “Medium Rare” challenge | Chongqing Guide | Dubai: on top of the world | Costume only, silent assassin guide
Best Weapons and Equipment | Mastery Items Unlocked
Vial of Emetic Poison: Level 5 Dubai Mastery - Poison that makes people sick - the target will leave the area after ingesting food / drink that has been poisoned and looking for a place to barf. Usually a private toilet.
Mallette ICA Mk. III: Level 7 Dubai Mastery - Briefcase that can hide a single object. Allows you to walk around with an additional illegal item without arousing suspicion.
Lockpick Mk. III: Level 2 Dartmoor Mastery - Used to unlock locked doors. Does not work on magnetic card doors or electronic locks.
Sedative poison vial: Level 7 Dartmoor Mastery - Much like the emetic poison, the sedative poison can be applied to food / drink and causes anyone who consumes it to sink into unconsciousness.
ICA Remote Micro Taser: Berlin Mastery Level 2 - Small remote device that shocks anyone in an area when activated. It's mic, so it won't be noticed by NPCs once placed.
Custom DTI 5mm: Level 7 Berlin Mastery - Special silent pistol that can be concealed during frisks. Small ammo counts and cannot be reloaded.
Vial of Deadly Poison: Level 10 Mastery Berlin - Precious poison that will kill anyone who ingests it immediately. Poison can be applied to food / drink, and death by poison counts as accidental death.
Hacker Mk. III dongle: Chongqing Level 2 Mastery - Single-use device that allows you to hack electronic locks. The only way to access certain areas without disguise.
Syringe for ICA Emetic pen: Level 5 Chongqing Mastery - Special emetic poison delivery item that looks like a pen. Allows you to poison drinks without arousing suspicion.
Kalmer 2 - Tranquilizer: Level 5 Mendoza Mastery - Powerful silent dart gun that seduces anyone you shoot unconsciously. Very useful for cleaning the guards without killing them.
Krugermeier 2-2 Silver: Level 10 Mendoza Mastery - Quietest silent pistol in the game. Ideal for use as a distraction tool.
Winner 300 Viper: Level 20 Mendoza Mastery - Silent Sniper Rifle, and the best in the game. Absolutely essential for Sniper Assassin races.
Hawke's Bay: night call | Silent Assassin, Costume Only | Miami: the finish line | Silent Assassin, Costume Only | Santa Fortuna: the three-headed serpent | Silent Assassin, Costume Only | Mumbai: in pursuit of a ghost | Silent Assassin, Costume Only | Whittleton Creek: Another Life | Silent Assassin, Costume Only | Sgail Island: The Ark Society | Silent Assassin, Costume Only | Haven Island - The Last Resort | Silent Assassin, Costume Only | How to enter the secret vault | Guide "It belongs to a museum"
